The administration of biological and chemical hazards to laboratory animals requires careful planning to prevent uncontrolled exposures for research, veterinary and animal husbandry staff. It is the Principal Investigator's responsibility to notify Laboratory Animal Resources  (LAR) prior to administering hazards. Prior notification provides time needed to educate students and staff involved in the care of the research animals on the precautions required to prevent exposure and inadvertent release of hazards into the environment.