Biological Toxins

Research involving biological toxins with a mammalian LD 50 of < 100 ug/kg body weight must be registered and approved by the Institutional Biosafety Committee.

Some biological toxins may be regulated by the Federal Select Agent Program, due to their potential to pose a severe threat to public health and safety. Possession, use, and transfer of these toxins is highly regulated. The complete list of Select Agents and Toxins can be found on this page, under Resources.

In small quantities, some of these toxins are exempt from select agent registration with the federal government.  Please note that possession, use, or transfer of any select agent toxin, in any quantity, must be registered with the IBC.

Exempt Quantities of Select Agent Toxins *


Quantity (mg)

Abrin 100
Conotoxin 100
Diacetoxyscirpenol(DAS) 1000
Ricin 100
Saxitoxin 100
Shiga-like ribisome activating proteins 100
Tetrodotoxin 100
Botulinum neurotoxins 0.5
Staphylococcal enterotoxins 5
Clostridium perfringens epsilon toxin 100
Shigatoxin 100
T-2 Toxin 100

* Select Agent Toxin in any quantity must be registered with the IBC.


Steve Elwood
Director for Research Safwey